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Once-weekly cagrilintide for weight management in people with overweight and obesity: A multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial

It is a small peptide complex that has attracted significant interest in laboratory and biochemical research due to its role in cellular signaling pathways

Its required for the production of red blood cells, the maintenance of the myelin sheath that protects nerve fibers, and the synthesis of DNA

The field awaits Phase 3 data to determine whether retatrutide's triple agonism translates into clinically meaningful advantages over the already substantial efficacy of tirzepatide

doi:10.1093/nutrit/nuu011