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The widely repeated claim that it is ~ten-million-fold more potent than BDNF is a relative in-vitro spine-counting ratio, not a human effect, and key mechanism papers from the originating lab were retracted in 2025

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This can be combated by simply reducing the dosage by half and increasing the frequency of the injections B12 shots should be taken on the same day of each week and every 7 days

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