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Chloramphenicol and other drugs having bone marrow suppressant properties may cause a lack of therapeutic response to vitamin B12

It is generally supplied within a Research Use Only framework for scientific research and must not be marketed with medicinal claims

A liver biopsy shows moderate inflammation with a lymphoplasmacytic infiltrate and interface hepatitis with stage 3 fibrosis

In aged skeletal muscle models, NNMT inhibitor treatment increased proliferating/active muscle stem cells by 60-75% following injury, myofiber cross-sectional area increased 1.8-fold at one week post-injury with high-dose treatment, and peak torque of injured muscle increased by 67% compared to control (p = 0.033), with no untoward systemic toxicity observed in plasma chemistry markers (Neelakantan et al., 2019)