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Defective fission-fusion dynamics, impaired mitophagic clearance, suppressed biogenesis, and disrupted proteostasis converge to produce bioenergetic failure, pathological ROS overproduction, calcium dyshomeostasis, and resistance to apoptosis, thereby transforming mitochondria from cellular powerhouses into drivers of lesion persistence and inflammation

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If you experience fatigue or symptoms associated with low vitamin B12 levels, speaking with a healthcare professional about a B12 deficiency injection may be helpful

Canada 1995