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2.3 System Xc - : cystine uptake and biosynthesis of GSH and polysulfides The supply of cysteine, the rate-limiting precursor for GSH, is maintained by the cystine/glutamate antiporter system Xc - , composed of SLC7A11 (also known as xCT) and SLC3A2 [76]

Unique attributes of orbital fibroblasts and global alterations in IGF-1 receptor signaling could explain thyroid-associated ophthalmopathy

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Antioxid Redox Signal 11 , 703714 (2009)