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In SURMOUNT-1 (NEJM 2022, 2,539 adults with obesity), the 15 mg arm averaged 22.5% body weight loss at 72 weeks, the 10 mg arm 21.4%, and the 5 mg arm 16.0%

Section 503A pharmacies (traditional compounding pharmacies) can still compound tirzepatide under limited circumstances when a prescriber documents that a patient requires a clinically significant modification, such as an alternative formulation due to allergy or intolerance to an inactive ingredient in the commercial product

Kidney disease has also been associated with vitamin B6 and B12 deficiency (Mariani 2014

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