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Unlike other markers of OS, this method allows for the direct evaluation of the ORP of seminal fluid, presenting numerous advantages, including a short duration, simplicity of execution, and the small volume of sample required [79]

[1] Picomolar activity is unusual for a small peptide and suggests high-affinity receptor-mediated signaling, though the specific receptor for GHK-Cu has never been identified

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However, superoxide and hydrogen peroxide play a physiological role in signaling molecules and regulate apoptosis, cell proliferation, and cell differentiation 18,19

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