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It also impairs osteoblast function by upregulating inhibitory proteins such as sclerostin (SOST) and Dickkopf-1 (DKK-1), which inhibit the Wnt/-catenin signaling pathway

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Measured parameters 2.5.1

Khasawneh A, Paran FJ, Oyama R, Maiti A, Abbas HA, Wang B, Desai PN, Hayes K, Harman JR, Su X, DiNardo CD, Andreeff M , Milne TA, Konopleva MY, Tabe Y

The survival rate of PC12 cells exposed to BDP-HPC rose from 48.0% to 94.4% following 2 h of NIR irradiation, suggesting that BDP-HPC could depolymerize A 42 fibrils and mitigate the cytotoxicity