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This risk is significant in persons who inject drugs, but reinfection can also occur through sexual contact, particularly among men who have sex with men (MSM).[40] In one study that clearly evaluated reinfection among treated PWID, the reinfection rate for those reporting ongoing injection after SVR was 5.3/100 person-years.[41] Similarly, in a recent systematic review of 36 studies of HCV reinfection following successful HCV treatment in persons who inject drugs, the overall rate of HCV reinfection was 6.2 per 100 person-years among those who reported recent injection drug use.[42] A similar systematic review and meta-analysis of 41 single-armed observational studies found a pooled rate of reinfection of 4.1 per 100 person-years), with a rate of reinfection of 2.8 per 100 person-years among PWID, 7.4 per 100 person-years among MSM, and 7.2 per 100 person-years among incarcerated individuals.[43] Thus, providing access to counseling for safe injection practices and MOUD is an important component of HCV treatment programs

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