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1998 JAMA 279 : 922929 Mao L, Lee J, Fan Y, Ro J, Batsakis J, Lippman S, Hittelman W, Hong W

For those with smoking initiation before depression onset, a positive association between the ages at smoking initiation and depression onset was observed, with a younger age at smoking initiation being associated with a younger age at depression onset (Fig

As noted in the 2025 Monitoring the Future survey, lifetime, annual, past month consumption, and binge drinking levels are below pre-pandemic levels and at historic low levels

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