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Even though liver biopsy is the gold standard for diagnosing cirrhosis, it usually is not necessary for patients who have other features of cirrhosis, such as portal hypertension

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It may promote the growth of new blood vessels and enhance cardiac function

Since this protein was shown to contain high levels of ordered secondary structure (49% -helical structure, 17% -structure, and 34% random coil structure) it was pointed out that clathrin, being characterized by a very large frictional ratio, cannot represent a random coil polypeptide chain, and it was therefore hypothesized that this protein consisted of several globular (likely -helical) domains connected by flexible polypeptide sequences to form a common locus (Pretorius et al., 1981)

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