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Likewise, ART specifically triggered ROS- and lysosomal iron-dependent cell death in pancreatic cancer cell (PDAC) lines (Lin et al., 2016

Metabolism of xenobiotics (xenobiotics - chemical components (drugs and poisons) foreign to the body) - Glutathione interacts with foreign chemicals (primarily, it is a scavenger of harmful xenobiotics that have been oxidized) compounds to neutralize and break them down, then eliminate them from the body

These factors underscore the importance of identifying strategies to enhance both the efficacy and tolerability of levodopa

The ratio of reduced glutathione (GSH) to its oxidized form (GSSG) serves as a fundamental marker of the intracellular redox environment