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While the drug initially showed promise in a Phase 2 study, a large Phase 3 trial failed to meet its primary endpoint, raising major doubts about efficacy.24 No trials of TUDCA alone have shown clear clinical benefit in ALS, and regulatory approvals for the combo have already been withdrawn in the U.S

Together with members of the caspase family, this equilibrium regulates apoptosis homeostasis [94]

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Ask about the recommended schedule some people benefit from weekly injections, while others only need them monthly