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[DOI] [PMC free article] [PubMed] [Google Scholar] 169.Scholte B.J., Horati H., Veltman M., Vreeken R.J., Garratt L.W., Tiddens H.A., Janssens H.M., Stick S

Cases of progressive gait instability and loss of balance have been documented in patients taking extremely high doses for extended periods, with symptoms in some instances proving irreversible

Yabut JM, Drucker DJ

Individuals With Chronic Tendon or Ligament Injuries Tendons and ligaments heal slowly due to limited blood supply and complex remodeling requirements

It appears to have been impactful in mice models of cardiac disease, where the life expectancy was reported to be increased by 27% compared to control animals