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One study, for instance, notes that people who are overweight or obese appear to have lower levels of vitamin B12 than those with a body mass index (BMI) that falls within the range considered to be normal. People who took vitamin B12 supplements of their own volition gained between 2.5 and 17 fewer pounds (1.27.7 kg) over ten years compared to those who did not take any form of supplementation with this vitamin

But the result has become an epidemic of too much B12

[17] Physiologic B12 requirements increase during gestation, and parenteral cyanocobalamin is considered appropriate when dietary intake or intestinal absorption is inadequate

No pharmacokinetic or pharmacodynamic interaction studies exist for the combination

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