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The following facts have been proven or are currently being discussed: Vitamin B1 (thiamine) does not have a direct effect on the skin, but its involvement in blood formation ensures rosy skin with good blood circulation Vitamin B2 (riboflavin) is important for keratinocytes and thus the skin barrier due to its positive effect on the fast-growing cells Niacin (vitamin B3) is an important vitamin for the protein metabolism, which is visible in the skin

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World J Gastroenterol 18(20):25112516 Lacey JM, Wilmore DW (1990) Is glutamine a conditionally essential amino acid

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Remove patches and dispense 2-3 drops of serum onto targeted dark spot areas 3