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The most commonly reported events in active arms were mild and transient: injection site reactions in some subcutaneous subjects, occasional headache, and in some oral dosing arms, minor gastrointestinal tolerance issues
used in long-term human clinical trials Intravenous injection Used primarily for pharmacokinetic characterization and acute dosing studies in humans Intraperitoneal injection Standard route for chronic rodent studies
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Some users report better subjective results with subcutaneous AOD 9604 than the oral formulation used in trials, but controlled data supporting those anecdotal reports does not exist at a level that would change the fundamental comparison