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Tumor-activated probe identifies metastases with spatial resolution To spatially detect the proteolytic activity in tissues, we designed a probe using the DNLGRAF substrate (MBvivo-DNLGRAF) that enables tissue retention of the probe upon cleavage through electrostatic interactions with a nearby cell membrane only after proteolytic activation (Fig

In Arabidopsis thaliana , much lower nitrogen levels were observed in senescing leaves than in pre-senescence leaves 5 , and nitrogen remobilizes from senescing leaves to storage organs or young expanding leaves 39