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GR may also play an important role in the regeneration of GSH from GSSG, due to the fact that GSH content has also been correlated with the concentration of some OCPs (endrin aldehyde, DDE and DDTs sum) (Table III)

Moreover, a reduction in pro-inflammatory cytokine IL-1-mediated vascular inflammation was observed in Nrf2-deficient ApoE -/- mice ( -/- and LDLR -/- mice expressing apoB-100 only (LDLR -/- ApoB 100/100 ) reduced atherosclerotic lesion development

[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Mercadal L., Tezenas du Montcel S., Chonchol M.B., Debure A., Depreneuf H., Servais A., Bassilios N., Assogba U., Allouache M., Pri D

When researchers gave mice NLY01 on day 12 after CPZ induction, they observed more regrowth, or remyelination, in the treated mice compared to the control group