Therefore, the problem that the agents successful in pre-clinical experimental autoimmune encephalitis trials, were either less effective in patients, worsened disease or caused unexpected, severe adverse events (60), may be at least partly solved with the more suited cuprizone model that reflects a toxic experimental model (12)
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Anything that is severe, worsening, or systemic is a reason to stop and seek a clinician rather than to adjust the protocol
No peptide option provides zero theoretical risk