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Calcified pineal tissue produces less melatonin

The foundation of peptide-based hair therapeutics dates back to 1973, when Loren Pickart first identified the tissue-regenerative properties of the copper-binding tripeptide GHK-Cu (glycyl-L-histidyl-L-lysine) [18,20,21]

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In vitro cultures of cisplatin-treated GCs to which metformin was added have displayed a significant reduction in the expression of senescence markers (p21, p16, and NF-B) and senescence-associated secretory phenotype (SASP) markers, IL-6 and IL-1, and in a number of senescence-associated beta-galactosidase (SA-gal)-staining cells, and ultimately, improved functional and structural changes occurred in cisplatin-induced POF mice (Lin et al., 2022)

LT + GSH treated plants including G1C, G2C and G3C have 1.8 fold, 2.14 fold, and 1.9 fold increase in SOD activity in comparison to that of LT stressed plants (Fig