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Older adults may experience age-related changes in their digestive system that reduce B12 uptake

Ann N Y Acad Sci

Cyanocobalamin is available in several dosage forms including the tablet, nasal spray, and injection

In the withdrawal trial, continuing preserved loss far better than switching to placebo, which regained about 14% over a year. The metabolic benefit fades in proportion to the weight regained, so a taper plus protein and resistance training beats a hard stop