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From 2010 to 2019, the total age-standardized incidence rate (ASR) of LC showed a decreasing trend, from 50.91/ 100000 in 2010 to 40.45/ 100000 in 2019 (APC= -1.5%, 95% CI: -2.70.3, p 0.05) and a significant downward trend in females (APC=-2.5%, 95% CI: -3.8 -1.3, p 0.05)

Metal/Metalloid Levels in Electronic Cigarette Liquids, Aerosols, and Human Biosamples: A Systematic Review