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For example, a live-attenuated parainfluenza vectored spike vaccine (B/HPIV3/S-6P) will be tested using a nasal spray for mucosal targeting after promising results were observed in nonhuman primates and hamsters [169, 170] (Table 3)

Jesu Arockiaraj, SRM Institute of Science and Technology, India Updates Copyright 2022 Choi, Taylor, Lee, Alhayek, Bechtel, Hamilton-Reeves, Spaeth, Adany and Sullivan

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The effects, monitoring needs, and risk profile can differ, so medical guidance matters.

Injectable preparations generally require stricter temperature control, while some oral and sublingual formats may be more temperature-tolerant due to the stabilizing excipients used in their formulation