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MRI findings in MERRF often reveal cerebellar and cerebral atrophy, focal white matter abnormalities, and bilateral symmetrical lesions in the brainstem, subthalamic nuclei, and basal ganglia (54)

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Rapamycins efficacy is further limited due to its metabolism via cytochrome P450 3A4 (Cyp3A4), which is induced by rifampin, complicating its use alongside standard TB treatments

And even individuals I know that have taken ozempic, a lot of those people are

doi:10.1111/j.1600-0722.1986.tb01364.x