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Additionally, while Occludin expression is frequently examined as a correlative measure of BBB dysfunction, the genetic loss of Occludin does not directly lead to increased permeability and loss of TJ integrity (Saitou et al., 2000)

However, the window has likely passed for the industry to use the referendum process to block the cigarette tax increase and other initiative campaigns from qualifying for the November ballot, as it had suggested it might (see below)

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* These have been prepared on a discrete basis, reflecting the revised useful economic lives in determining the terminal value applied