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Tobacco smoking as a possible etiologic factor in bronchiogenic carcinoma: A study of 684 proved cases

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PLACK: peeling skin, leukonychia, acral punctate keratosis, cheilitis, and knuckle pads (piel descamada, leuconiquia, keratosis puntada acral, queilitis y almohadillas en los nudillos)

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Table of Contents HOW SMOKING CAUSES WRINKLES AND PREMATURE AGEING Smoking leads to wrinkles and premature aging by a couple of mechanisms, like reducing blood flow and reducing oxygen carrying capacity of the blood which prevents the skin cells from being supplied with all the nutrients they need