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0-12 h, time-course 0-12 h) regulates the mRNA and protein levels of GSS in OGD/R-treated PC12 cells, promotes nuclear translocation of Nrf2 in cells, reduces the interaction between Nrf2 and Keap1, inhibits the upregulation of Keap1, decreases MDA and Fe 2+ levels, improves cell viability, and thereby inhibits ferroptosis in cells [6]

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Qiu ZQ, Deng ZJ, Tan HM, Zhou SN, Cao LX