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This, in turn, led to a substantial reduction in energy metabolism in Huh7 and Hep3B cells

While B12 can be stored in your liver for up to five years, you can become deficient (lacking) in it if you don't get enough

10.1002/dc.23838 76 KisielJ

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Common hallmark traits include: Long-term low mood that rarely lifts fully Persistent low energy Low self-esteem Reduced motivation Trouble concentrating or making decisions A sense of hopelessness that has become background Many people with PDD describe their mood as "just how I am." That is part of what makes the condition easy to miss