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To use cannabis and avoid the harmful effects of smoke, consider an alternative method

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In: How tobacco smoke causes disease: the biology and behavioral basis for smoking-attributable disease: a report of the surgeon general

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It has been recently reported that cigarette smoke is associated with the upregulation of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) protein expression and activity in granulosa cells of women undergoing in vitro fertilization (Leslie et al., 2015)