In addition to being highly addictive, nicotine can result in increased blood pressure, heart rate, blood flow to the heart, constriction of arteries, and heart attacks due to the hardening of arterial walls
The concentration of 1 mg/mL is equivalent to about 6 mM for the lactones, 7 mM for actinidine, 5.5 mM for dihydroactinidiolide, 6.5 mM for menthol and methyl salicylate, 4 mM for civetone, and 8.5 mM for indole
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Symptoms of nicotine withdrawal often decrease over 1 month