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Multiple clinical features of the disease, including intestinal barrier disintegration and mucosal immune activation, may be modulated by sex hormones, as shown in both clinical and experimental models (249)

Neuroendocrine and stress-axis research (exploring peptide-linked signaling patterns tied to stress physiology)

bFGF, which is one of the 22 different isotypes of FGF, plays a crucial role in the wound healing process by promoting fibroblast proliferation, inducing neovascularization, and increasing the synthesis of collagenase

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