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Nicotinic receptors and nicotines effect on the brain Commercially available products, including cigarettes, nicotine replacement therapies (NRTs), smoke-free products, and others, contain levels of nicotine high enough to temporarily affect brain function in a reversible way
The Cooper and Haney (2009) study documented measurable differences in plasma THC, exhaled carbon monoxide, and subjective intoxication between the two formats under controlled conditions
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