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This suggests that GPx blood activity may be a parameter contributing to the identification of subclinical asymptomatic cardiometabolic disorders [14]

Patients with MCS exhibit elevated oxidative status and inflammatory markers compared to their healthy counterparts.[ref] MCS patients also have lower glutathione levels.[ref] Glutathione is a naturally produced antioxidant and one of the main ways that our cells fight oxidative stress

Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress

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These pathways compensate for the survival benefits when the classic GPX4-dependent system is impaired