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Your body becomes addicted to nicotine after prolonged use of tobacco causes your body to compensate for these increases in adrenaline, dopamine, serotonin, norepinephrine, and other neurotransmitters and hormones

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Of all the lungs cell types, these are among the most likely to become cancerous. Mutations Caused by Smoking The researchers found that mutations (single-nucleotide variants and small insertions and deletions) accumulated in the lung cells of non-smokers as they ageand that significantly more mutations were found in the lung cells of the smokers