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We previously demonstrated that specific Trkb deletion in iSPNs resulted in age-dependent hyperlocomotor dysfunction, consistent with early hyperkinetic symptoms in HD

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More specifically, the following groups are most likely to see benefit from consistent use: People with insulin resistance or metabolic risk factors Because inositol-derived molecules participate in insulin signaling, supplementation has been studied in people with insulin resistance, impaired glucose regulation, and related metabolic risk

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7,9,10 Limitation: most of that literature uses clinic-depth needling for scars and photoaging