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The 15-amino-acid fragment designated BPC-157 was selected for study because it retained the cytoprotective properties of the parent protein while being amenable to chemical synthesis at research-grade purity a practical advantage that has enabled three decades of systematic preclinical investigation
Additionally, electrophysiological experiments have shown the direct effects of B vitamins on pain transmission pathways in the spinal cord and thalamus, which explains the observed reduction or loss of pain sensation in clinical patients
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