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Current research on DAN has advanced diagnostic tools and treatment strategies, but the understanding of its complex mechanisms and the impact of gut microbiota remains insufficient

In controlled lighting studies involving rodents subjected to constant illumination (a stressor that disrupts circadian patterns), intermittent Epithalon treatment normalized melatonin and cortisol rhythms, partially preserving typical daynight physiological cycles [2][4][5]

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They are not approved for human or veterinary use by the FDA, EMA, or any other regulatory authority