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3.3 Biochemical and urinary parameters Adenine and STZ caused a significant decrease in plasma calcium levels and significantly increased phosphorus, uric acid, urea, and creatinine plasma levels (Table 2)

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The value of GSH and nutritional strategies like amino acids, vitamins, minerals, phytochemicals, sulforaphane to enhance cellular Nrf2, and other supplements used to restore GSH levels (Minich and Brown, 2019

Hydration and barrier renewal: Niacinamide refines texture and strengthens the outer barrier, whilst Ceramide NP locks in moisture