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Your best choice depends on your budget, tolerance for side effects, and how quickly you want to see results

It's prescribed for patients with confirmed vitamin B12 deficiency, especially those who cannot absorb B12 properly from food or oral supplements

(2014) Fructose-1,6-bisphosphatase opposes renal carcinoma progression, Nature , 513 , 251-255, doi: Anderton, B., Camarda, R., Balakrishnan, S., Balakrishnan, A., Kohnz, R

Looking at all studies is valuable for providing an overview of all research, important to avoid cherry-picking, and informative when a positive result is found despite combining less-optimal situations