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Propolis extract and its bioactive compoundsfrom traditional to modern extraction technologies

scale-up does not change the upstream production processes 82,85

The results indicated that in mice on the diet supplemented with cholestyramine, which depletes bile acids, APAP toxicity was exacerbated, whereas those on a diet supplemented with cholic acid had a more rapid recovery from APAP

Glutathione contains anti-inflammatory properties

Moreover, ferroptosis can propagate through intercellular mechanisms involving the release of damage-associated molecular patterns (DAMPs), dysregulation of immune checkpoints, and exosome-mediated signaling, collectively driving microglial activation, T-cell infiltration, and bloodbrain barrier disruption, culminating in systemic immune imbalance