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doi: 10.1152/ajpregu.00778.2006 183

Atopic dermatitis in the pediatric population: a cross-sectional, international epidemiologic study

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In summary, activation of NRF2 can effectively regulate the function of chondrocytes, synovial macrophages, synovial fibroblasts, and osteoclasts, thereby effectively inhibiting synovial inflammation, protecting cartilage and subchondral bone, alleviating joint pain, and serving as a potential target for treating OA