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Components of this module had the closest hits to those in Clostridium, Epulopiscium , and Vallitalea with a range of 5174% amino acid sequence identity

The cDNA sequences for wild-type human hepsin (hHPN WT ) and a loss-of-function mutant (hHPN RS

Cysteine can become a limiting factor for the synthesis of GSH

Glutamine-addicted ccRCC tumors deprive the tumor microenvironment of glutamine

H 2 O 2 produced during the oxidative folding of endoplasmic reticulum proteins has been found to regulate the signal transduction process of nuclear factor E2-related factor 2 (Nrf2), which in turn regulates the expression of downstream glutathione peroxidase 8 (GPX8), which in turn can participate in ER calcium regulation through endoplasmic reticulum calcium ATPase (SERCA) (Figure 7)