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The cyanide produced from the metabolism of cyanocobalamin is not lethal but it will still require effort and energy by the body to get rid of it

Subcutaneous administration (which bypasses first-pass metabolism and delivers more peptide to target tissues) was not extensively tested in human trials, and this route is what most current research protocols use

[18] Follow any disposal instructions on the label or given by the pharmacy, or return the unused medication to a take-back program if available

While our bodies can store B12 for years, some groups are more susceptible to deficiency, often because of absorption issues rather than diet

Patients with mild, recently developed deficiency typically respond more rapidly than those who have been deficient for months or years