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3b), despite neurons expressed mito GCL, indicating that GPx1 use of -glutamylcysteine is essential for -glutamylcysteine-mediated O 2 detoxification in this model of excitotoxicity

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NO modulates mitochondrial biogenesis also during myocytes differentiation by S-nitrosylation-mediated activation of the transcription factor CREB (cAMP response element-binding protein), which efficiently binds to the PGC-1a gene promoter region increasing its concentration and downstream signaling events [76]

Steroids In more severe cases of APD, steroids (or corticosteroids) can be prescribed to manage acute APD flare-ups

This could be poor air quality, it could be pesticides, like glyphosate, chemicals in our food, in our water