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data curation, writingoriginal draft preparation

The incidence of apoptosis, along with the depletion of circulating B-lymphocytes and the upregulation of Treg cells post-labrylase administration, proposes that this recombinant uricase treatment for HUA might influence outcomes by inhibiting B-cells to bolster Treg (102)

This mechanism is particularly relevant for Indian skin tones, where UV exposure and pollution significantly accelerate pigmentation concerns

The peptide is currently sold for research purposes only and lacks FDA approval for human therapeutic use

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