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In addition, a study by Numis et al

High glucose and advanced glycation end-product levels result in an obvious upregulation in the expression of intercellular adhesion molecules and vascular cell adhesion molecules, increased leukocyte adhesion to and migration across brain microvascular endothelial cell monolayers, and elevated BBB leakage in in vitro model with brain microvascular endothelial cells [79]

Facts 14 , 568576 (2021)

Balen AH, Morley LC, Misso M, et al

Chronic PASC is a cumulative outcome of at least 10 different HMRD-related pathophysiological mechanisms involving both virus-derived virulence factors and a multitude of innate host responses