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[1] Neurosyphilis and ocular syphilis may also be present during this stage and others, depending on the initial point of infection: Neurosyphilis The infection spreads to the brain and spinal cord and may lead to meningeal syphilis (headache, stiff neck, nausea, and vomiting), meningovascular syphilis (headache, stiff neck, nausea, vomiting, and risk of stroke), general paresis (personality or mood changes), or tabes dorsalis (muscle failure and pain and impaired balance)

It can suppress breathing and is linked to overdose

Cell Prolif 40(1): 125-141, 2007

The young man had a history of using e-cigarettes for many years and had previously been hospitalised for e-cigarette poisoning in 2023