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Similar to the data in BEAS-2B, increased Complex V levels were accompanied by increased Mn-SOD protein levels in PBECs from COPD patients, which may reflect a compensatory mechanism in response to increased energy demand and/or elevated oxidative stress (Figure 5A)

A prior study highlighted that innovative strategy utilizing digital tools and behavioral insights have demonstrated potential in decreasing worldwide tobacco consumption 34

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[5] Frank Newport, Young People Adopt Vaping as Their Smoking Rate Plummets, Gallup, July 26, 2018, [6] U.S