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The primary proponent of marital immigration was the Virginia Company treasurer Edwin Sandys, who successfully convinced his fellow board members that this was the best way to increase the colonys female population, make the men more setled [and] lesse moveable, and decrease the number who stay [in the colony] but to gett something and then return for England. Sandyss harder task was persuading potential brides to come to Jamestown

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The background risk of other major birth defects and miscarriage for the indicated population are unknown